Anti-FGF1 monoclonal antibody, clone 5E3

Antibody Isotype

IgG1

Clone

5E3

Species Reactivity

Human; Monkey

Immunogen

Recombinant full length mature Human FGF1 alpha corresponding to amino acids 16-155, produced in E.coli, (NP_000791).

Conjugate

Application Notes

WB: 1/5000 - 1/50000; ICC/IF: 1/100;

Alternative Names

FGF1; fibroblast growth factor 1 (acidic); FGFA; fibroblast growth factor 1; AFGF; ECGF; ECGF beta; ECGFA; ECGFB; endothelial cell growth factor; alpha; beta; FGF alpha; GLIO703; HBGF1; heparin binding growth factor 1; heparin-binding growth factor 1; bet

Entrez Gene ID

UniProt ID

Antigen Description

The heparin-binding fibroblast growth factors play important roles in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. They are potent mitogens in vitro.

Pathway

Downstream signaling of activated FGFR, organism-specific biosystem; FGF signaling pathway, organism-specific biosystem; FGFR ligand binding and activation, organism-specific biosystem; FGFR1 ligand binding and activation, organism-specific biosystem; FGFR1b ligand binding and activation, organism-specific biosystem; FGFR1c ligand binding and activation, organism-specific biosystem; FGFR2 ligand binding and activation, organism-specific biosystem;