Anti-FGF1 monoclonal antibody (DCABH-546)

Mouse anti-Human FGF1 monoclonal antibody for WB, ICC/IF Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
5E3
Species Reactivity
Human, Monkey
Immunogen
Recombinant full length mature Human FGF1 alpha corresponding to amino acids 16-155, produced in E.coli, (NP_000791).
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/5000 - 1/50000; ICC/IF: 1/100;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
FGF1; fibroblast growth factor 1 (acidic); FGFA; fibroblast growth factor 1; AFGF; ECGF
Entrez Gene ID
UniProt ID

Product Background


Pathway
Downstream signaling of activated FGFR, organism-specific biosystem; FGF signaling pathway, organism-specific biosystem; FGFR ligand binding and activation, organism-specific biosystem; FGFR1 ligand binding and activation, organism-specific biosystem; FGFR1b ligand binding and activation, organism-specific biosystem; FGFR1c ligand binding and activation, organism-specific biosystem; FGFR2 ligand binding and activation, organism-specific biosystem;

Citations


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References


Henriksson, ML; Edin, S; et al. Colorectal Cancer Cells Activate Adjacent Fibroblasts Resulting in FGF1/FGFR3 Signaling and Increased Invasion. AMERICAN JOURNAL OF PATHOLOGY 178:1387-1394(2011).
Davol, PA; Frackelton, AR; et al. Targeting human prostatic carcinoma through basic fibroblast growth factor receptors in an animal model: Characterizing and circumventing mechanisms of tumor resistance. PROSTATE 40:178-191(1999).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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