This product (Catalog No. DPABH-08854) is a rabbit-derived polyclonal antibody raised against human FFAR2. This antibody exhibits cross-reactivity with Human FFAR2 from pig. It has been affinity purified by Protein A. Free fatty acid receptors (FFAR) play significant roles in various physiological processes through interaction with their ligands, fatty acids. Free fatty acid receptor 2 (FFAR2, also known as FFA2 or GPR43) is a receptor for short-chain fatty acids (SCFAs) and plays a role in the regulation of whole-body energy homeostasis and intestinal immunity (PMID: 12684041). It has been considered a therapeutic target for metabolic and inflammatory conditions (PMID: 23589301). FFAR2 has a calculated molecular weight of 37 kDa and can be glycosylated. The higher apparent molecular weight of 50 kDa has been reported, probably due to glycosylation (PMID: 31707282; 28131568). DPABH-08854 is suitable for use in Western blot (WB) (1:500–1:1,000), IHC (1:50–1:500) applications. DPABH-08854 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
Target
Alternative Names
FFA2; FFA2R; free fatty acid receptor 2; G protein coupled receptor 43; GPCR43
A: DPABH-08854 antibodies store at 4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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