Anti-FCRL1 monoclonal antibody (DCABH-11549) Made to order

Rabbit anti-Human FCRL1 monoclonal antibody for WB, ELISA

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Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
A synthetic peptide of human FCRL1 is used for rabbit immunization.
Conjugate
Unconjugated

Target


Alternative Names
FCRL1; Fc receptor-like 1; Fc receptor-like protein 1; CD307a; FCRH1; IFGP1
Entrez Gene ID
UniProt ID

Product Background


Gene summary
FCRL1 (Fc Receptor Like 1) is a Protein Coding gene. An important paralog of this gene is FCRL2. This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein contains three extracellular C2-like immunoglobulin domains, a transmembrane domain and a cytoplasmic domain with two immunoreceptor-tyrosine activation motifs. This protein may play a role in the regulation of cancer cell growth. Alternative splicing results in multiple transcript variants.
Antigen Description
This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein contains three extracellular C2-like immunoglobulin domains, a transmembrane domain and a cytoplasmic domain with two immunoreceptor-tyrosine activation motifs. This protein may play a role in the regulation of cancer cell growth. Alternative splicing results in multiple transcript variants. May function as an activating coreceptor in B-cells. May function in B-cells activation and differentiation. Fc receptor-like protein 1 is a protein that in humans is encoded by the FCRL1 gene. 0The function about FCRL1 antigen include receptor activity.

Citations


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We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Du, X; Nagata, S; et al. FCRL1 on chronic lymphocytic leukemia, hairy cell leukemia, and B-cell non-Hodgkin lymphoma as a target of immunotoxins. BLOOD 111:338-343(2008).
Baranov, KO; Volkova, OY; et al. Expression of human B-Cell specific receptor FCRL1 in healthy individuals and in patients with autoimmune diseases. MOLECULAR BIOLOGY 46:450-456(2012).

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