Anti-FCGR2B monoclonal antibody (DCABY-4095)

Rat Anti-Mouse FCGR2B monoclonal antibody for WB, ELISA(Cap) Datasheet

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Specifications


Host Species
Rat
Antibody Isotype
IgG2a
Clone
200008
Species Reactivity
Mouse
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse Fc gamma RIIB. aa 40-217 Accession Number P08101
Conjugate
Unconjugated

Applications


Application Notes
Western Blot: 1 μg/mL; ELISA Capture: 2-8 μg/mL; ELISA Detection: 0.1-0.4 μg/mL
We recommend the following for sandwich ELISA (Capture - Detection):
DCABY-4095 - DPABY-456
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
FCGR2B; Fc receptor, IgG, low affinity IIb; CD32; Fcgr2; Fcr-2; Fcr-3
Entrez Gene ID
UniProt ID

Product Background


Pathway
B Cell Receptor Signaling Pathway; B cell receptor signaling pathway; FCGR activation; Fc gamma R-mediated phagocytosis; Fcgamma receptor (FCGR) dependent phagocytosis; Immune System; Innate Immune System; Measles;

Citations


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References


Sakai, T; Kogiso, M; et al. Deletion polymorphisms in the promoter region of Fc-gamma receptor IIB is not associated with antigen-specific IgG2a and IgG2b antibody responses in NC/Nga mice. MICROBIOLOGY AND IMMUNOLOGY 50:475-480(2006).
Li, FB; Ravetch, JV; et al. Apoptotic and antitumor activity of death receptor antibodies require inhibitory Fc gamma receptor engagement. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 109:10966-10971(2012).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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