Anti-FCGR2B monoclonal antibody (DCABY-4095)
Rat Anti-Mouse FCGR2B monoclonal antibody for WB, ELISA(Cap)
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Mouse myeloma cell line NS0-derived recombinant mouse Fc gamma RIIB. aa 40-217 Accession Number P08101
Western Blot: 1 μg/mL; ELISA Capture: 2-8 μg/mL; ELISA Detection: 0.1-0.4 μg/mL
We recommend the following for sandwich ELISA (Capture - Detection):
DCABY-4095 - DPABY-456
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
FCGR2B; Fc receptor, IgG, low affinity IIb; CD32; Fcgr2; Fcr-2; Fcr-3
B Cell Receptor Signaling Pathway; B cell receptor signaling pathway; FCGR activation; Fc gamma R-mediated phagocytosis; Fcgamma receptor (FCGR) dependent phagocytosis; Immune System; Innate Immune System; Measles;
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Chen, JY; Wang, CM; et al. A transmembrane polymorphism in Fc gamma RIIb (FCGR2B) is associated with the production of anti-cyclic citrullinated peptide autoantibodies in Taiwanese RA. GENES AND IMMUNITY 9:680-688(2008).
Treon, SP; Yang, G; et al. Attainment of complete/very good partial response following rituximab-based therapy is an important determinant to progression-free survival, and is impacted by polymorphisms in FCGR3A in Waldenstrom macroglobulinaemia. BRITISH JOURNAL OF HAEMATOLOGY 154:223-228(2011).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.