Specifications
Immunogen
A synthetic peptide of human FBXW9 is used for rabbit immunization.
Target
Alternative Names
FBXW9; F-box and WD repeat domain containing 9; F box and WD 40 domain protein 9; F-box/WD repeat-containing protein 9; Fbw9; MGC10870; F-box and WD-40 domain protein 9; F-box and WD-40 domain-containing protein 9; F-box and WD-40 repeat containing protei
Product Background
Antigen Description
Members of the F-box protein family, such as FBXW9, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).
Pathway
Association of TriC/CCT with target proteins during biosynthesis, organism-specific biosystem; Chaperonin-mediated protein folding, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem; Protein folding, organism-specific biosystem.
Citations
Publication ()
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