Anti-FBXO6 polyclonal antibody

Species Reactivity

Human

Immunogen

A synthetic peptide corresponding to human FBXO6. The sequence is C-EAAQSPYRAVVQIF

Conjugate

Application Notes

ELISA: 1:8000. & The optimal working dilution should be determined by the end user.

Alternative Names

FBXO6; F-box protein 6; FBG2; FBS2; FBX6; Fbx6b; F-box only protein 6; F-box protein FBG2; F-box protein Fbx6; F-box/G-domain protein 2; F-box protein that recognizes sugar chains 2;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class, and its C-terminal region is highly similar to that of rat NFB42 (neural F Box 42 kDa) which may be involved in the control of the cell cycle.

Pathway

Adaptive Immune System; Proteasome degradation; Chaperonin-mediated protein folding; presentation.