Anti-FBXO30 monoclonal antibody (DCABH-11529) Made to order

Rabbit anti-Human FBXO30 monoclonal antibody for WB, ELISA

View other FBXO30 antibodies

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
A synthetic peptide of human FBXO30 is used for rabbit immunization.
Conjugate
Unconjugated

Target


Alternative Names
FBXO30; F-box protein 30; F box only protein, helicase, 18; F-box only protein 30; Fbx30; MGC21674
Entrez Gene ID
UniProt ID

Product Background


Gene summary
FBXO30 (F-Box Protein 30) is a Protein Coding gene. Diseases associated with FBXO30 include nasopharyngeal carcinoma. GO annotations related to this gene include ubiquitin-protein transferase activity. An important paralog of this gene is FBXO40. This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it is upregulated in nasopharyngeal carcinoma.
Antigen Description
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it is upregulated in nasopharyngeal carcinoma. Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Required for muscle atrophy following denervation. The function about FBXO30 antigen include metal ion binding; ubiquitin-protein ligase activity; zinc ion binding.

Citations


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We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Sartori, R; Schirwis, E; et al. BMP signaling controls muscle mass. NATURE GENETICS 45:1309-+(2013).
Ayala-Figueroa, JM; Flores, N; et al. Identification and Expression Analysis of Two Homologs from Xenopus laevis of the Tumorhead Putative Binding Protein, FBXO30. FASEB JOURNAL 27:-(2013).

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