Anti-FBXO27 monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human FBXO27 is used for rabbit immunization.

Conjugate

Alternative Names

FBXO27; F-box protein 27; F box only protein 27; F-box only protein 27; Fbg5; Fbx27; F-box protein FBG5; F-box/G-domain protein 5; FBG5;

Entrez Gene ID

UniProt ID

Antigen Description

Members of the F-box protein family, such as FBXO27, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).

Pathway

Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Immune System, organism-specific biosystem;