Synthetic peptide corresponding to a region within C-terminal amino acids 239-288 (ELLLALSSEK HVRLEHLRID VVSENPGQTH FHTIQKSSWD AFIKHSPKVN) of Mouse FBXL3 (NP_056637).
Conjugate
Unconjugated
Target
Alternative Names
FBXL3; F-box and leucine-rich repeat protein 3; F box and leucine rich repeat protein 3A; FBXL3A; F-box/LRR-repeat protein 3; FBL3; FBL3A; F-box protein Fbl3a; F-box/LRR-repeat protein 3A; F-box and leucine-rich repeat protein 3A; FBXL3A;
Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex involved in circadian clock function. The SCF(FBXL3) complex acts by mediating ubiquitination and subsequent degradation of CRY1 and CRY2. Recruiter of target protein that may recognize and bind to some phosphorylated proteins and promotes their ubiquitination and degradation.
Pathway
Association of TriC/CCT with target proteins during biosynthesis; Chaperonin-mediated protein folding; Circadian Clock; Circadian rhythm - mammal; Metabolism of proteins; Protein folding;
Citations
Publication ()
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