Anti-FBXL21 (aa 167-276) polyclonal antibody

Species Reactivity

Human

Immunogen

FBXL21 (NP_036291, 167 a.a. ~ 276 a.a) partial recombinant protein with GST tag. The sequence is VSKVVLGRVGLNCPRLIELVVCANDLQPLDNELICIAEHCTNLTALGLSKCEVSCSAFIR FVRLCERRLTQLSVMEEVLIPDEDYSLDEIHTEVSKYLGRVWFPDVMPLW

Conjugate

Alternative Names

FBXL21; F-box and leucine-rich repeat protein 21 (gene/pseudogene); FBL3B; Fbl21; FBXL3B; FBXL3P; F-box/LRR-repeat protein 21; F-box protein Fbl3b; F-box/LRR-repeat protein 3B; F-box and leucine-rich repeat protein 3B; F-box and leucine-rich repeat protei

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains 6 tandem leucine-rich repeats. The amino acid sequence of this protein is highly similar to that of f-box and leucine-rich repeat protein 3A. Comparisons of this gene to orthologous sequences suggest that it may be a pseudogene, and may no longer express a functional protein.[provided by RefSeq, Aug 2009]