Anti-FASN monoclonal antibody (DCABH-2066) Knockout Validated

Rabbit anti-Human FASN monoclonal antibody for WB, FC, ICC/IF

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Clone
FQS8576
Species Reactivity
Mouse, Rat, Human
Immunogen
Synthetic peptide from a region of Human Fatty Acid Synthase
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/1000 - 1/10000; Flow Cyt: 1/10 - 1/100; ICC/IF: 1/250 - 1/500.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
FASN; fatty acid synthase; FAS; SDR27X1; short chain dehydrogenase/reductase family 27X; member 1
Entrez Gene ID
UniProt ID

Product Background


Pathway
ChREBP activates metabolic gene expression, organism-specific biosystem; Fatty Acid Biosynthesis, organism-specific biosystem; Fatty Acyl-CoA Biosynthesis, organism-specific biosystem; Fatty acid biosynthesis, organism-specific biosystem; Fatty acid biosynthesis, conserved biosystem; Fatty acid biosynthesis, elongation, organism-specific biosystem; Fatty acid biosynthesis, elongation, conserved biosystem;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Oliveras-Ferraros, C; Vazquez-Martin, A; et al. AMPK-sensed cellular energy state regulates the release of extracellular Fatty Acid Synthase. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 378:488-493(2009).
Xue, T; Zhang, Y; et al. Proteomic Analysis of Two Metabolic Proteins with Potential to Translocate to Plasma Membrane Associated with Tumor Metastasis Development and Drug Targets. JOURNAL OF PROTEOME RESEARCH 12:1754-1763(2013).

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