Anti-FAM65B polyclonal antibody (DPABH-20459)

Rabbit anti-Human FAM65B (aa 765-863) polyclonal antibody for IHC-P

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
antigen sequence: TPFVARSLLE KLSRQIQVME KLAAVSDENI GNISSVVEAI PEFHKKLSLL SFWTKCCSPV GVYHSPADRV MKQLEASFAR TVNKEYPGLA DPVFRTLVS, corresponding to amino acids 765-863 of Human FAM65B.
Conjugate
Unconjugated

Applications


Application Notes
IHC-P: 1/1000.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
FAM65B; family with sequence similarity 65, member B; C6orf32, chromosome 6 open reading frame 32; protein FAM65B; DIFF48; KIAA0386
Entrez Gene ID
UniProt ID

Product Background


Gene summary
FAM65B (Family With Sequence Similarity 65 Member B) is a Protein Coding gene. Diseases associated with FAM65B include deafness, autosomal recessive 104 and autosomal recessive non-syndromic sensorineural deafness type dfnb. GO annotations related to this gene include binding. An important paralog of this gene is FAM65A. The protein encoded by this gene stimulates the formation of a non-mitotic multinucleate syncytium from proliferative cytotrophoblasts during trophoblast differentiation. Alternative splicing of this gene results in multiple transcript variants.
Antigen Description
Isoform 2 play a role in promoting myogenic cell differentiation, cytoskeletal rearrangement and filopodia formation. Deafness, autosomal recessive, 104 (DFNB104) [MIM:616515]: A form of non-syndromic sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. Note=The disease is caused by mutations affecting the gene represented in this entry. The function about FAM65B antigen include binding.

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Taipalensuu, J; Falk, A; et al. A wound- and methyl jasmonate-inducible transcript coding for a myrosinase-associated protein with similarities to an early nodulin. PLANT PHYSIOLOGY 110:483-491(1996).

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