Anti-FAM13A (aa 904-973) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

antigen sequence: TDFSARCFLD QFEDDADGFI SPMDDKIPSK CSQDTGLSNL HAASIPELLE HLQEMREEKK RIRKKLRDFE, corresponding to C terminal amino acids 904-973 of Human FAM13A protein (UniProt ID: O94988).

Conjugate

Application Notes

IHC-P: 1/500 - 1/1000. WB: 1/250 - 1/500.

Alternative Names

FAM13A; family with sequence similarity 13, member A; FAM13A1; ARHGAP48; protein FAM13A; FAM13A1_v2 protein; family with sequence similarity 13, member A1;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Pathway

Rho GTPase cycle; Signaling by Rho GTPases;