General Notes
This product (Catalog No. DPABH-08860) is a rabbit-derived IgG polyclonal antibody raised against human FADS2, targeting the amino acid region 221–300 of the protein. This antibody exhibits cross-reactivity with FADS2 from mouse, rat, chicken, pig, cow, horse, and rabbit. It has been affinity purified by Protein A. The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization. Alternative splicing results in multiple transcript variants encoding different isoforms.
DPABH-08860 is suitable for use in Western blot (WB) (1:500–1:2,000) application.
DPABH-08860 is supplied as a liquid formulation in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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