Anti-EXTL3 polyclonal antibody (DPABH-03803)

Rabbit Anti-Human EXTL3 (aa 295-621) polyclonal antibody for WB, IHC-P Datasheet

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Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
Recombinant fragment corresponding to a region within internal sequence amino acids 295-621 of Human EXTL3 (UniProt ID: O43909).
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/500 - 1/3000; IHC-P: 1/100 - 1/1000.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
EXTL3; exostoses (multiple)-like 3; exostosin-like 3; botv; REG receptor; REGR
Entrez Gene ID
UniProt ID

Product Background


Pathway
Activation of Chaperone Genes by XBP1(S); Activation of Chaperones by IRE1alpha; Diabetes pathways; Disease; Glycosaminoglycan biosynthesis - heparan sulfate; Glycosaminoglycan biosynthesis, heparan sulfate backbone;

Citations


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References


Souza, ARC; Kozlowski, EO; et al. Chondroitin sulfate and keratan sulfate are the major glycosaminoglycans present in the adult zebrafish Danio rerio (Chordata-Cyprinidae). GLYCOCONJUGATE JOURNAL 24:521-530(2007).
Van Ba, IAT; Marchal, S; et al. Regenerating Islet-derived 1 alpha (Reg-1 alpha) Protein Is New Neuronal Secreted Factor That Stimulates Neurite Outgrowth via Exostosin Tumor-like 3 (EXTL3) Receptor. JOURNAL OF BIOLOGICAL CHEMISTRY 287:4726-4739(2012).

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