Anti-EXOC5 monoclonal antibody (DCABH-11469) Made to order

Rabbit anti-Human EXOC5 monoclonal antibody for WB, ELISA

View other EXOC5 antibodies

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
A synthetic peptide of human EXOC5 is used for rabbit immunization.
Conjugate
Unconjugated

Target


Alternative Names
EXOC5; exocyst complex component 5; SEC10 (S. cerevisiae) like 1 , SEC10 like 1 (S. cerevisiae) , SEC10L1; SEC10; SEC10P; SEC10-like 1
Entrez Gene ID
UniProt ID

Product Background


Gene summary
EXOC5 (Exocyst Complex Component 5) is a Protein Coding gene. Among its related pathways are Transport to the Golgi and subsequent modification and Arf6 trafficking events. GO annotations related to this gene include protein N-terminus binding and Ral GTPase binding. The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity.
Antigen Description
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Exocyst complex component 5 is a protein that in humans is encoded by the EXOC5 gene. The function about EXOC5 antigen include protein N-terminus binding.
Pathway
Arf6 trafficking events, organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem; Insulin Pathway, organism-specific biosystem; Insulin Synthesis and Processing, organism-specific biosystem.

Citations


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We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Gonzalez, IM; Ackerman, WE; et al. Exocyst complex protein expression in the human placenta. PLACENTA 35:442-449(2014).
Zhang, XY; Orlando, K; et al. Membrane association and functional regulation of Sec3 by phospholipids and Cdc42. JOURNAL OF CELL BIOLOGY 180:145-158(2008).

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