Anti-ETFDH monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human ETFDH is used for rabbit immunization.

Conjugate

Alternative Names

ETFDH; electron-transferring-flavoprotein dehydrogenase; electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial; ETFQO; ETF-QO; ETF dehydrogenase; ETF-ubiquinone oxidoreductase; electron transfer flavoprotein ubiquinone oxidoreductase; MA

Entrez Gene ID

UniProt ID

Antigen Description

Electron-transferring-flavoprotein dehydrogenase in the inner mitochondrial membrane accepts electrons from electron-transfer flavoprotein which is located in the mitochondrial matrix and reduces ubiquinone in the mitochondrial membrane. The protein is synthesized as a 67-kDa precursor which is targeted to mitochondria and processed in a single step to a 64-kDa mature form located in the mitochondrial membrane. Deficiency in electron-transferring-flavoprotein dehydrogenase have been demonstrated in some patients with type II glutaricacidemia.

Pathway

Metabolism, organism-specific biosystem; Respiratory electron transport, organism-specific biosystem; Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins., organism-specific biosystem; The citric acid (TCA) cycle and respiratory electron transport, organism-specific biosystem;