Fusion protein corresponding to residues near the N terminal of human epithelial stromal interaction 1
Conjugate
Unconjugated
Applications
Application Notes
WB: 1:1000-1:5000
General Notes
This product (Catalog No. DPABH-10317) is a rabbit-derived IgG polyclonal antibody raised against human EPSTI1. It has been affinity purified by protein A. The protein encoded by this gene has been shown to promote tumor invasion and metastasis in some invasive cancer cells when overexpressed. Expression of this gene has been shown to be upregulated by direct binding of the Kruppel like factor 8 protein to promoter sequences. The translated protein interacts with the amino terminal region of the valosin containing protein gene product, resulting in the nuclear translocation of the nuclear factor kappa B subunit 1 gene product, and activation of target genes. Overexpression of this gene has been observed in some breast cancers and in some individuals with systemic lupus erythematosus (SLE). DPABH-10317 is suitable for use in Western blot (WB) (1:1,000–1:5,000) application. DPABH-10317 is supplied as a liquid formulation in pH7.4 PBS, 0.05% sodium azide, 40% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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