Specifications
Immunogen
A synthetic peptide of human EPHX2 is used for rabbit immunization.
Target
Alternative Names
EPHX2; epoxide hydrolase 2, cytoplasmic; epoxide hydrolase 2; epoxide hydratase; epoxide hydrolase, soluble; epoxide hydrolase 2, cytosolic; CEH; SEH;
Product Background
Antigen Description
This gene encodes a member of the epoxide hydrolase family. The protein, found in both the cytosol and peroxisomes, binds to specific epoxides and converts them to the corresponding dihydrodiols. Mutations in this gene have been associated with familial hypercholesterolemia. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
Pathway
Arachidonate Epoxygenase / Epoxide Hydrolase, organism-specific biosystem; Arachidonic acid metabolism, organism-specific biosystem; Arachidonic acid metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem; Peroxisome, organism-specific biosystem; Peroxisome, conserved biosystem;
Citations
Publication ()
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