Anti-EPHB6 (aa 23-122) polyclonal antibody

Species Reactivity

Human

Immunogen

EPHB6 (NP_004436, 23 a.a. ~ 122 a.a) partial recombinant protein with GST tag. The sequence is DTTGETSEIGWLTYPPGGWDEVSVLDDQRRLTRTFEACHVAGAPPGTGQDNWLQTHFVER RGAQRAHIRLHFSVRACSSLGVSGGTCRETFTLYYRQAEE

Conjugate

Alternative Names

EPHB6; EPH receptor B6; HEP; ephrin type-B receptor 6; tyrosine-protein kinase-defective receptor EPH-6; human kinase-defective Eph-family receptor protein;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a member of a family of transmembrane proteins that function as receptors for ephrin-B family proteins. Unlike other members of this family, the encoded protein does not contain a functional kinase domain. Activity of this protein can influence cell adhesion and migration. Expression of this gene is downregulated during tumor progression, suggesting that the protein may suppress tumor invasion and metastasis. Alternative splicing results in multiple transcript variants.

Pathway

Axon guidance;