Anti-EPHA4 (aa 887-986) polyclonal antibody

Species Reactivity

Human

Immunogen

EPHA4 (NP_004429, 887 a.a. ~ 986 a.a) partial recombinant protein with GST tag. The sequence is SLKRTGTESSRPNTALLDPSSPEFSAVVSVGDWLQAIKMDRYKDNFTAAGYTTLEAVVHV NQEDLARIGITAITHQNKILSSVQAMRTQMQQMHGRMVPV

Conjugate

Alternative Names

EPHA4; EPH receptor A4; SEK; HEK8; TYRO1; ephrin type-A receptor 4; EK8; EPH-like kinase 8; TYRO1 protein tyrosine kinase; tyrosine-protein kinase TYRO1; tyrosine-protein kinase receptor SEK; receptor protein-tyrosine kinase HEK8;

Entrez Gene ID

UniProt ID

Antigen Description

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.

Pathway

Axon guidance; EphrinA-EPHA pathway;