Synthetic peptide corresponding to a region within internal amino acids 138-187 (VACHLGVLTE LPCIGVAKKL LQVDGLENNA LHKEKIVLLQ AGGDTFPLIG) of Mouse Endonuclease V (isoform 1, NP_001158108).
Selectively cleaves DNA at the second phosphodiester bond 3 to hypoxanthine- and uracil-containing nucleotides. Shows higher activity towards single-stranded than double-stranded DNA and towards hypoxanthine than uracil.
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