Anti-EMR4P (aa 21-93) polyclonal antibody

Species Reactivity

Human

Immunogen

EMR4 (XP_377506, 21 a.a. ~ 93 a.a) partial recombinant protein with GST tag. The sequence is GSEAKNSGASCPPCPKYASCHNSTHCTCEDGFRARSGRTYFHDSSEKCEDINECETGLAK CKYKAYCRNKVGG

Conjugate

Alternative Names

EMR4P; egf-like module containing, mucin-like, hormone receptor-like 4 pseudogene; EMR4; FIRE; PGR16; GPR127;

Entrez Gene ID

Antigen Description

This gene is a member of the EGF-TM7 receptor gene family which is thought to play a role in leukocyte adhesion and migration. In other vertebrates, including nonhuman primates, this gene encodes a protein containing N-terminal EGF domains and a C-terminal transmembrane domain. Sequence evidence for the human gene, however, indicates nucleotide deletion in the genomic sequence would result in frameshift and early termination of translation. A protein expressed by this gene would be soluble rather than expressed on the cell surface. As the encoded protein has not been detected, this gene may represent a transcribed pseudogene.