Rabbit anti-Mouse Elf4/MEF polyclonal antibody

The garden pea has been a model for the genetics of flowering for several decades and numerous flowering loci have been identified, but until recently little was known about the molecular nature of these loci. This paper presents an update on recent work on the molecular genetics of flowering in pea, outlining progress in gene and mutant isolation, expression analyses, grafting and other physiological studies, and candidate gene assessment. Work so far has led to the identification of the LATE1 and DNE loci as orthologues of Arabidopsis GIGANTEA and ELF4, respectively, and candidate genes for several other loci are being evaluated. Expression analysis of an expanded FT-like gene family suggests a more complex role for this group of genes. These results provide the first insight into the circadian clock, photoperiod response mechanism, and mobile signals in pea, and identify both conserved and divergent features in comparison with Arabidopsis.

Oral cancer is a noteworthy issue in the Indian subcontinent where it positions among the main three kinds of tumour in the nation. Cancer starts in the squamous cell because uncontrollable growth occurs in the squamous cell, which is known as squamous cell carcinoma. Gradual growth of cancer may lead to the invasion of deeper tissues. ELF4 is a transcription factor belonging to the ETS family which can suppress tumors and can remain inactive in the body for a broad class of tumors found in human. With the help of high throughput ChIP-Seq data, we analyzed the transcription factor binding regions of ELF4 using standard procedures for quality check, sequence alignment, peak calling and motif discovery. The outcome of this study was the identification of several genes that could be used as potential targets and biomarkers for oral cancer with thorough investigation.