Specifications
Species Reactivity
Mouse; Rat; Human; Xenopus laevis
Immunogen
Synthetic peptide, corresponding to a region within HuR/ ELAVL1.
Applications
Application Notes
Flow Cyt: 1μg/106 cells.
Target
Alternative Names
ELAVL1; ELAV like RNA binding protein 1; HUR; Hua; MelG; ELAV1; ELAV-like protein 1; Hu antigen R; hu-antigen R; embryonic lethal, abnormal vision, drosophila, homolog-like 1; ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R);
Product Background
Antigen Description
Involved in 3-UTR ARE-mediated MYC stabilization. Binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, HUR binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA and AUUUUUA motifs.
Pathway
Gene Expression, organism-specific biosystem; Regulation of mRNA Stability by Proteins that Bind AU-rich Elements, organism-specific biosystem; Stabilization of mRNA by HuR, organism-specific biosystem;
Citations
Publication ()
Have you cited DCABH-3270 in a publication?
Let us know and earn a reward for your research.
COA
Loading ......
