Specifications
Immunogen
A synthetic peptide of human EIF2C4 is used for rabbit immunization.
Target
Alternative Names
EIF2C4; eukaryotic translation initiation factor 2C, 4; protein argonaute-4; AGO4; argonaute 4; FLJ20033; KIAA1567; hAgo4; eIF2C 4; eIF-2C 4; argonaute4;
Product Background
Antigen Description
This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic containing PAZ and PIWI domains, and it may play a role in short-interfering-RNA-mediated gene silencing. This gene is located on chromosome 1 in a cluster of closely related family members including argonaute 3, and eukaryotic translation initiation factor 2C, 1.
Pathway
Gene Expression, organism-specific biosystem; MicroRNA (miRNA) Biogenesis, organism-specific biosystem; Post-transcriptional Silencing By Small RNAs, organism-specific biosystem; Pre-NOTCH Expression and Processing, organism-specific biosystem; Pre-NOTCH Transcription and Translation, organism-specific biosystem; Regulatory RNA pathways, organism-specific biosystem; Signal Transduction, organism-specific biosystem.
Citations
Publication ()
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