Rabbit Anti-Human EI24 (a.a. 267-340) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Recombinant human EI24 protein; Source: E. coli derived, PGEX-4T; Tag: GST; Domain: 267-340 aa of BC002390

Conjugate

Application Notes

WB: 1:500-1:2000
IHC: 1:50-1:500

General Notes

This product (Catalog No. DPABH-24826) is a rabbit-derived polyclonal antibody raised against human EI24, targeting the amino acid region 267–340 of the protein. It has been affinity purified by Protein A. Ei24 is an ER-localized protein originally identified as a p53-induced proapoptotic gene in etoposide-treated NIH3T3 cells. It has been shown to be able to bind to the antiapoptotic protein Bcl-2 (PMID: 15781622), play a role in autophagy (PMID: 23074225), and induce proliferate arrest/apoptosis (PMID: 10594026). Ei24 can bind specifically to IMPβ1 and IMPα2 to impede their normal role in nuclear import (PMID: 24821838).
DPABH-24826 is suitable for use in Western blot (WB) (1:500–1:2,000), IHC (1:50–1:500) applications.
DPABH-24826 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

etoposide induced 2.4 mRNA; Etoposide-induced protein 2.4 homolog; p53 induced gene 8 protein; p53-induced factor Ei24; p53-induced gene 8 protein

Entrez Gene ID

UniProt ID