Anti-EGR2 monoclonal antibody, clone 2H6

Antibody Isotype

IgG2b

Clone

2H6

Species Reactivity

Human; Rat

Immunogen

EGR2 (NP_000390.2, 217 a.a. ~ 293 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Conjugate

Alternative Names

EGR2; early growth response 2; early growth response 2 (Krox 20 homolog, Drosophila) , KROX20; E3 SUMO-protein ligase EGR2; Krox 20 homolog; Drosophila; zinc finger protein Krox-20; early growth response protein 2; KROX-20, Drosophila, homolog (early grow

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene is a transcription factor with three tandem C2H2-type zinc fingers. Defects in this gene are associated with Charcot-Marie-Tooth disease type 1D (CMT1D), Charcot-Marie-Tooth disease type 4E (CMT4E), and with Dejerine-Sottas syndrome (DSS). Multiple transcript variants encoding two different isoforms have been found for this gene.

Pathway

Adipogenesis, organism-specific biosystem; Calcineurin-regulated NFAT-dependent transcription in lymphocytes, organism-specific biosystem; Developmental Biology, organism-specific biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem; IL4-mediated signaling events, organism-specific biosystem; Transcriptional Regulation of White Adipocyte Differentiation, organism-specific biosystem;