Recombinant protein corresponding to amino acids of human EFCAB6. The sequence is QQSTEKAVAARDKLMDRHQDISKAFTKTDQSKTNYISICKMQEVLEECGCSLTEGELTHL LNSWGVSRHDNAINYLDFLRAVENSKSTGAQPKEKEESMPINFATLNPQEVVRKIQEVVE SSQLALSTAFSALDKEDT
Conjugate
Unconjugated
Applications
Application Notes
IHC: 1:200-1:500. & The optimal working dilution should be determined by the end user.
Target
Alternative Names
EFCAB6; EF-hand calcium binding domain 6; DJBP; HSCBCIP1; dJ185D5.1; EF-hand calcium-binding domain-containing protein 6; DJ-1-binding protein; CAP-binding protein complex-interacting protein 1;
This gene encodes a protein which directly binds the oncogene DJ-1 and androgen receptor to form a ternary complex in cells. This binding protein recruits histone-deacetylase complexes in order to repress transcription activity of androgen receptor. This protein may also play a role in spermatogenesis and fertilization. Multiple transcript variants encoding different isoforms have been found for this gene.
Pathway
Androgen receptor signaling pathway;
Citations
Publication ()
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COA
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