Rabbit Anti-Human EDARADD (a.a. 1-215) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Recombinant human EDARADD protein; Source: E. coli derived, PGEX-4T; Tag: GST; Domain: 1-215 aa of BC128082

Conjugate

Application Notes

WB: 1:2000-1:12000

General Notes

This product (Catalog No. DPABH-22046) is a rabbit-derived polyclonal antibody raised against human EDARADD, targeting the amino acid region 1–215 of the protein. It has been affinity purified by Protein A. EDARADD (EDAR-associated death domain) is an adaptor protein that mediates the interaction between the extracellular Ectodysplasin A receptor (EDAR) and intracellular signaling components, orchestrating a series of downstream events that regulate key biological processes such as cell proliferation, differentiation, and apoptosis. EDARADD is a 25 KDa death domain-containing adaptor protein. EDARADD was shown to interact with TRAF1, -2 and -3 as well as with TAB2 (TAK1-binding protein 2) and is therefore likely to be responsible for coupling receptor activation with engagement of the NF-κB pathway (PMID: 23845861).
DPABH-22046 is suitable for use in Western blot (WB) (1:2,000–1:12,000) application.
DPABH-22046 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

Ectodysplasin-A receptor-associated adapter protein; EDAR-associated death domain protein; Protein crinkled homolog

Entrez Gene ID

UniProt ID