Specifications
Species Reactivity
Human; Mouse; Rat
Immunogen
A synthesized peptide derived from human DYNLRB1
Applications
Application Notes
WB: 1:1000-3000
General Notes
This product (Catalog No. DPABH-25472) is a rabbit-derived polyclonal antibody raised against human DYNLRB1. This antibody exhibits cross-reactivity with DYNLRB1 from mouse and rat. It has been affinity purified by Protein A. This gene is a member of the roadblock dynein light chain family. The encoded cytoplasmic protein is capable of binding intermediate chain proteins, interacts with transforming growth factor-beta, and has been implicated in the regulation of actin modulating proteins. Upregulation of this gene has been associated with hepatocellular carcinomas, suggesting that this gene may be involved in tumor progression. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 12 and 18.
DPABH-25472 is suitable for use in Western blot (WB) (1:1,000–1:3,000) application.
DPABH-25472 is supplied as a liquid formulation in PBS containing 50% glycerol, and 0.02% sodium azide. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
Target
Alternative Names
DYNLRB1, BITH, BLP, DNCL2A, Dynein-associated protein Km23, ROBLD1, Roadblock domain containing 1, Bithoraxoid-like protein, DNLC2A, Roadblock-1, ROBL/LC7-like 1
Citations
Publication ()
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