General Notes
This product (Catalog No. DPABH-06824) is a rabbit-derived polyclonal antibody raised against human DYNC1LI2, targeting the amino acid region 1–492 of the protein. This antibody exhibits cross-reactivity with Human DYNC1LI2 from mouse and rat. It has been affinity purified by Protein A. Cytoplasmic dynein is a microtubule-associated motor protein. DYNC1LI2 (Cytoplasmic dynein 1 light intermediate chain 2), also known as LIC2, belongs to the dynein light intermediate chain family. DYNC1LI2 acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. It may play a role in binding dynein to membranous organelles or chromosomes. Northern blot analysis of rat tissues detected high expression of DYNC1LI2 in skeletal muscle, testis, heart, lung, and brain, and lower expression in liver, kidney, and spleen (PMID: 7738094).
DPABH-06824 is suitable for use in Western blot (WB) (1:500–1:1,000), IHC (1:50–1:500) applications.
DPABH-06824 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.