Anti-DUSP16 monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human DUSP16 is used for rabbit immunization.

Conjugate

Alternative Names

DUSP16; dual specificity phosphatase 16; dual specificity protein phosphatase 16; KIAA1700; MAPK phosphatase 7; MKP 7; MKP7; MAPK phosphatase-7; MAP kinase phosphatase 7; mitogen-activated protein kinase phosphatase 7; MKP-7; FLJ36298; FLJ40991; MGC129701

Entrez Gene ID

UniProt ID

Antigen Description

The activation of mitogen-activated protein kinase (MAPK) cascades transduces various extracellular signals to the nucleus to induce gene expression, cell proliferation, differentiation, cell cycle arrest, and apoptosis. For full activation of MAPKs, dual-specificity kinases phosphorylate both threonine and tyrosine residues in MAPK TXY motifs. MKPs are dual-specificity phosphatases that dephosphorylate the TXY motif, thereby negatively regulating MAPK activity.

Pathway

MAPK signaling pathway, organism-specific biosystem; MAPK signaling pathway, conserved biosystem; Regulation of p38-alpha and p38-beta, organism-specific biosystem;