This product (Catalog No. DPABH-08575) is a rabbit-derived polyclonal antibody raised against human DTWD1. It has been affinity purified by Protein A. DTWD1 (DTW domain-containing protein 1) is a novel tumor suppressor gene and RNA modification enzyme primarily responsible for catalyzing the formation of acp3U (3-(3-amino-3-carboxypropyl)uridine) at position 20 in the D-loop of cytoplasm-localized tRNAs. It is down-regulated in gastric cancer, acts via HDAC3 regulation, and inhibits cell proliferation. DPABH-08575 is suitable for use in IHC (1:25–1:100) application. DPABH-08575 is supplied as a liquid formulation in pH7.4 PBS, 0.05% sodium azide, 40% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
Target
Alternative Names
DTW domain containing 1; DTW domain-containing protein 1; Dtwd1; DTWD1_HUMAN; MDS009; x 009 protein
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