This gene encodes the D4 subtype of the dopamine receptor.The D4 subtype is a G-protein coupled receptor which inhibitsadenylyl cyclase. It is a target for drugs which treatschizophrenia and Parkinson disease. Mutations in this gene havebeen associated with various behavioral phenotypes, includingautonomic nervous system dysfunction, attentiondeficit/hyperactivity disorder, and the personality trait ofnovelty seeking. This gene contains a polymorphic number (2-10copies) of tandem 48 nt repeats; the sequence shown contains fourrepeats.
Pathway
Amine ligand-binding receptors; Class A/1 (Rhodopsin-like receptors); Dopamine receptors; Dopaminergic synapse; G alpha (i) signalling events; GPCR downstream signaling; GPCR ligand binding; GPCRs, Class A Rhodopsin-like;
Citations
Publication ()
Have you cited DCABY-1093 in a publication? Let us know and earn a reward for your research.
My Review for Anti-DRD4 monoclonal antibody, clone 736DU2.6.5
Creative Diagnostics products are for RESEARCH USE ONLY, please make sure your review is research based.
Required fields are marked with *
Terms and conditions:
We will select high-quality review customers and offer a $30 coupon for your next purchase.
All product reviews must be submitted in the English language.
Creative Diagnostics will not share any personal information of applicants, and all information will be treated with strict confidentiality and will not be sold or disclosed to a third party.
COA
Publication 
Loading ......
