Recombinant fusion protein of human Dopamine Receptor D3 (Dopamine Receptor D3 (DRD3)) (NP_000787.2).
Conjugate
Unconjugated
Applications
Application Notes
WB: 1:500-1:2000 IF: 1:50-1:200
General Notes
This product (Catalog No. DPABH-22319) is a rabbit-derived polyclonal antibody raised against human DRD3. This antibody exhibits cross-reactivity with DRD3 from mouse and rat. It has been affinity purified by Protein A. This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD). DPABH-22319 is suitable for use in Western blot (WB) (1:500–1:2,000), IF (immunofluorescence) (1:50–1:200) applications. DPABH-22319 is supplied as a liquid formulation in PBS with 0.02% sodium azide,50% glycerol,pH7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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