Anti-DRAP1 (aa 1-30) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Synthetic peptide within Human NC2 alpha aa 1-30 (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.Database link: Q14919

Conjugate

Application Notes

WB: 1/100 - 1/500;

Alternative Names

DRAP1; DR1-associated protein 1 (negative cofactor 2 alpha); NC2-alpha; dr1-associated corepressor; negative cofactor 2 alpha; negative cofactor 2-alpha; negative co-factor 2-alpha;

Entrez Gene ID

UniProt ID

Antigen Description

This gene was identified on the basis of its stimulation by c-Myc protein. The latter is a transcription factor that participates in the regulation of cell proliferation, differentiation, and apoptosis. The exact function of this gene is not known but studies in rat suggest a role in cellular proliferation and c-Myc-mediated transformation. Two alternative transcripts encoding different proteins have been described.

Pathway

Developmental Biology; Signaling by Activin;