DPH2 (NP_001375, 125 a.a. ~ 235 a.a) partial recombinant protein with GST tag. The sequence is RQRSVALELCVKAFEAQNPDPKAPVVLLSEPACAHALEALATLLRPRYLDLLVSSPAFPQ PVGSLSPEPMPLERFGRRFPLAPGRRLEEYGAFYVGGSKASPDPDLDPDLS
Conjugate
Unconjugated
Target
Alternative Names
DPH2; DPH2 homolog (S. cerevisiae); DPH2L2; diphthamide biosynthesis protein 2; DPH2-like 2; diphthamide biosynthesis-like protein 2; diphthamide biosynthesis protein 2 homolog-like 2; diptheria toxin resistance protein required for diphthamide biosynthes
This gene is one of two human genes similar to the yeast gene dph2. The yeast gene was identified by its ability to complement a diphthamide mutant strain, and thus probably functions in diphthamide biosynthesis. Diphthamide is a post-translationally modified histidine residue present in elongation factor 2 (EF2) that is the target of diphtheria toxin ADP-ribosylation. Two transcript variants encoding different isoforms have been found for this gene.
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