Anti-DPEP3 polyclonal antibody (DPABH-25095)

Rabbit anti-Human DPEP3 (aa 394-424) polyclonal antibody for WB Datasheet

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Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Mouse, Human
Immunogen
Synthetic peptide conjugated to KLH, corresponding to C terminal amino acids 394-424 of Human DPEP3 (NP_001123230.1)
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/100 - 1/500
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
DPEP3; dipeptidase 3; MBD3; membrane-bound dipeptidase 3; metallopeptidase (family M19)
Entrez Gene ID
UniProt ID

Product Background


Gene summary
DPEP3 (Dipeptidase 3) is a Protein Coding gene. Among its related pathways are Gene Expression and Metabolism. GO annotations related to this gene include peptidase activity and metalloexopeptidase activity. An important paralog of this gene is DPEP2. This gene encodes a membrane-bound glycoprotein from the family of dipeptidases involved in hydrolytic metabolism of various dipeptides, including penem and carbapenem beta-lactam antibiotics. This gene is located on chromosome 16 in a cluster with another member of this family. Alternatively spliced transcript variants that encode different isoforms have been found for this gene.
Antigen Description
Probable metalloprotease which hydrolyzes cystinyl-bis-glycine. May be involved in meiosis. May be involved in meiosis (By similarity). Dipeptidase 3 (DPEP3) is a protein that in humans is encoded by the DPEP3 gene. 0The function about DPEP3 antigen include dipeptidase activity; dipeptidyl-peptidase activity; metal ion binding; metalloexopeptidase activity.

Citations


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References


Yoshitake, H; Yanagida, M; et al. Molecular characterization and expression of dipeptidase 3, a testis-specific membrane-bound dipeptidase: complex formation with TEX101, a germ-cell-specific antigen in the mouse testis. JOURNAL OF REPRODUCTIVE IMMUNOLOGY 90:202-213(2011).

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