Specifications
Immunogen
A synthetic peptide of human DNAJC5 is used for rabbit immunization.
Target
Alternative Names
DNAJC5; DnaJ (Hsp40) homolog, subfamily C, member 5; ceroid lipofuscinosis, neuronal 4 (Kufs disease) , CLN4; dnaJ homolog subfamily C member 5; DNAJC5A; FLJ00118; FLJ13070; cysteine string protein alpha; CSP; NCL; CLN4; CLN4B; DKFZp434N1429; DKFZp761N122
Product Background
Antigen Description
This gene is a member of the J protein family. J proteins function in many cellular processes by regulating the ATPase activity of 70 kDa heat shock proteins. The encoded protein plays a role in membrane trafficking and protein folding, and has been shown to have anti-neurodegenerative properties. The encoded protein is known to play a role in cystic fibrosis and Huntingtons disease. A pseudogene of this gene is located on the short arm of chromosome 8.
Pathway
GABA synthesis, release, reuptake and degradation, organism-specific biosystem; Neuronal System, organism-specific biosystem; Neurotransmitter Release Cycle, organism-specific biosystem; Protein processing in endoplasmic reticulum, organism-specific biosy
Citations
Publication ()
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COA
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