Specifications
Immunogen
Synthetic peptide: EVKKHQNQEDRC (Human) from the internal region of the protein sequence according to NP_000784.2; NP_054644.1; NP_001007024.1.
Applications
Application Notes
WB: 0.05 μg/ml; IHC-Fr: 2 - 3 μg/ml.
Target
Alternative Names
DIO2; deiodinase, iodothyronine, type II; type II iodothyronine deiodinase; SelY; thyroxine deiodinase; type II; TXDI2; type 2 DI; type-II 5deiodinase; type-II 5-deiodinase; thyroxine deiodinase, type II; type 2 iodothyronine deiodinase; D2; 5DII; DIOII;
Product Background
Antigen Description
Responsible for the deiodination of T4 (3,5,3,5-tetraiodothyronine) into T3 (3,5,3-triiodothyronine). Essential for providing the brain with appropriate levels of T3 during the critical period of development.
Pathway
Amine-derived hormones; Metabolism; Metabolism of amino acids and derivatives; Regulation of thyroid hormone activity; Selenium Metabolism and Selenoproteins; Selenium Pathway; Thyroxine biosynthesis
Citations
Publication ()
Have you cited DPABH-17812 in a publication?
Let us know and earn a reward for your research.
COA
Loading ......
