Recombinant protein corresponding to human DGCR14. The sequence is LRVEGSETPYVDRTPGPAFKILEPGRRERLGLKMANEAAAKNRAKKQEALRRVTENLASL TPKGLSPAMSPALQRLVSRTASKYTDRALRASYTPSPARSTHLKTPASGLQTPTSTPAPG SATRTPLTQDPASITDNL
Conjugate
Unconjugated
Applications
Application Notes
WB: 1:250-1:500; IHC-P: 1:50-1:200. & The optimal working dilution should be determined by the end user.
Target
Alternative Names
DGCR14; DiGeorge syndrome critical region gene 14; ES2; DGSH; DGSI; DGS-H; DGS-I; Es2el; DGCR13; protein DGCR14; Protein DGCR13; DiGeorge syndrome gene H; DiGeorge syndrome gene I; diGeorge syndrome protein H; diGeorge syndrome critical region 13; diGeorg
This gene is located within the minimal DGS critical region (MDGCR) thought to contain the gene(s) responsible for a group of developmental disorders. These disorders include DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome, and some familial or sporadic conotruncal cardiac defects which have been associated with microdeletion of 22q11.2. The encoded protein may be a component of C complex spliceosomes, and the orthologous protein in the mouse localizes to the nucleus.
Citations
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COA
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