Recombinant fragment, corresponding to a region within amino acids 92-242 of Human DECR2
Conjugate
Unconjugated
Applications
Application Notes
WB: 1/500 - 1/3000; IHC-P: 1/100 - 1/1000.
Target
Alternative Names
DECR2; 2,4-dienoyl CoA reductase 2, peroxisomal; peroxisomal 2,4-dienoyl-CoA reductase; PDCR; SDR17C1; short chain dehydrogenase/reductase family 17C; member 1; 2,4-dienoyl-CoA reductase 2; short chain dehydrogenase/reductase family 17C, member 1;
Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Has activity towards short and medium chain 2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19-docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid.
Pathway
Peroxisome;
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
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Gurvitz, A; Rottensteiner, H; et al. The Saccharomyces cerevisiae peroxisomal 2,4-dienoyl-CoA reductase is encoded by the oleate-inducible gene SPS19. JOURNAL OF BIOLOGICAL CHEMISTRY 272:22140-22147(1997).
KOIVURANTA, KT; HAKKOLA, EH; et al. ISOLATION AND CHARACTERIZATION OF CDNA FOR HUMAN 120 KDA MITOCHONDRIAL 2,4-DIENOYL-COENZYME-A REDUCTASE. BIOCHEMICAL JOURNAL 304:787-792(1994).
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COA
Certificate of Analysis