General Notes
This product (Catalog No. DPABH-24771) is a rabbit-derived polyclonal antibody raised against human DDX4. This antibody exhibits cross-reactivity with DDX4 from mouse and rat. It has been affinity purified by Protein A. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a homolog of VASA proteins in Drosophila and several other species. The gene is specifically expressed in the germ cell lineage in both sexes and functions in germ cell development. Multiple transcript variants encoding different isoforms have been found for this gene.
DPABH-24771 is suitable for use in Western blot (WB) (1:200–1:2,000), IHC (1:50–1:200), IF (immunofluorescence) (1:50–1:200) applications.
DPABH-24771 is supplied as a liquid formulation in PBS with 0.02% sodium azide, 50% glycerol, pH7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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