Specifications
Immunogen
Recombinant fragment, corresponding to a region within amino acids 229 - 413 of Human DDX39 (O00148).
Applications
Application Notes
WB: 1/500 - 1/3,000; IHC-P: 1/100 - 1/500.
Target
Alternative Names
DDX39A; DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A; BAT1; DDXL; BAT1L; DDX39; URH49; ATP-dependent RNA helicase DDX39A; DEAD box protein 39; nuclear RNA helicase URH49; UAP56-related helicase, 49 kDa; DEAD (Asp-Glu-Ala-Asp) box polypeptide 39; DEAD/H (Asp
Product Background
Antigen Description
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX39 encodes a member of this family. The function of this member has not been determined. Alternative splicing of this gene generates 2 transcript variants encoding different isoforms.
Citations
Publication ()
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