Anti-DDX25 monoclonal antibody (DCABH-11247) Made to order

Rabbit anti-Human DDX25 monoclonal antibody for WB, ELISA

View other DDX25 antibodies

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
A synthetic peptide of human DDX25 is used for rabbit immunization.
Conjugate
Unconjugated

Target


Alternative Names
DDX25; DEAD (Asp-Glu-Ala-Asp) box helicase 25; DEAD (Asp Glu Ala Asp) box polypeptide 25 , DEAD/H (Asp Glu Ala Asp/His) box polypeptide 25; ATP-dependent RNA helicase DDX25; gonadotropin regulated testicular RNA helicase; GRTH
Entrez Gene ID
UniProt ID

Product Background


Gene summary
DDX25 (DEAD-Box Helicase 25) is a Protein Coding gene. Diseases associated with DDX25 include hydrolethalus syndrome. GO annotations related to this gene include nucleic acid binding and helicase activity. An important paralog of this gene is DDX19B. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. The encoded protein is a gonadotropin-regulated and developmentally expressed testicular RNA helicase. It may serve to maintain testicular functions related to steroidogenesis and spermatogenesis.
Antigen Description
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. The encoded protein is a gonadotropin-regulated and developmentally expressed testicular RNA helicase. It may serve to maintain testicular functions related to steroidogenesis and spermatogenesis. ATP-dependent RNA helicase. Required for mRNA export and translation regulation during spermatid development (By similarity). The function about DDX25 antigen include ATP binding; ATP-dependent RNA helicase activity; ATPase activity; RNA binding; hydrolase activity; nucleotide binding.

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We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Sheng, Y; Tsai-Morris, CH; et al. Gonadotropin-regulated testicular RNA helicase (GRTH/Ddx25) is a transport protein involved in gene-specific mRNA export and protein translation during spermatogenesis. JOURNAL OF BIOLOGICAL CHEMISTRY 281:35048-35056(2006).

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