Rabbit Anti-Human DCTD (a.a. 1-178) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse; Rat

Immunogen

Recombinant human DCTD protein; Source: E. coli derived, PGEX-4T; Tag: GST; Domain: 1-178 aa of BC001286

Conjugate

Application Notes

WB: 1:500-1:2000
IF/ICC: 1:50-1:500

General Notes

This product (Catalog No. DPABH-24145) is a rabbit-derived polyclonal antibody raised against human DCTD, targeting the amino acid region 1–178 of the protein. This antibody exhibits cross-reactivity with Human DCTD from mouse and rat. It has been affinity purified by Protein A. DCTD(Deoxycytidylate deaminase) is also named as dCMP deaminase and belongs to the cytidine and deoxycytidylate deaminase family. It catalyzes the deamination of dCMP to dUMP, thus providing the nucleotide substrate for thymidylate synthase. Control of deaminase activity at this juncture in deoxyribonucleotide metabolism is determined by the ratio of dCTP to dTTP in the cell, since the enzyme is allosterically activated by dCTP and inhibited by dTTP(PMID:7685356). It has 2 isoforms produced by alternative splicing and can exsit as a dimer(pMID:8798492).
DPABH-24145 is suitable for use in Western blot (WB) (1:500–1:2,000), IF/ICC (1:50–1:500) applications.
DPABH-24145 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

dCMP deaminase; DCTD; Deoxycytidylate deaminase

Entrez Gene ID

UniProt ID