This product (Catalog No. DPABH-12132) is a rabbit-derived polyclonal antibody raised against human DCAF8. This antibody exhibits cross-reactivity with DCAF8 from mouse and rat. It has been affinity purified by Protein A. DCAF8 (DDB1- and Cul4-associated factor 8) is a substrate adaptor protein for the Cul4-RING E3 ubiquitin ligase (CRL4) complex, acting as a critical regulator in protein degradation. It plays a key role in maintaining hematopoietic stem cell (HSC) function, cellular senescence, and spermatogenesis. Its expression declines with age, leading to increased DNA damage and loss of stem cell function. DPABH-12132 is suitable for use in Western blot (WB) (1:1,000–1:2,000) application. DPABH-12132 is supplied as a liquid formulation in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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