Fusion protein corresponding to residues near the C terminal of human dachshund homolog 2 (Drosophila)
Conjugate
Unconjugated
Applications
Application Notes
IHC: 1:50-1:200
General Notes
This product (Catalog No. DPABH-15501) is a rabbit-derived IgG polyclonal antibody raised against human DACH2. It has been affinity purified by protein A. This gene is one of two genes which encode a protein similar to the Drosophila protein dachshund, a transcription factor involved in cell fate determination in the eye, limb and genital disc of the fly. The encoded protein contains two characteristic dachshund domains: an N-terminal domain responsible for DNA binding and a C-terminal domain responsible for protein-protein interactions. This gene is located on the X chromosome and is subject to inactivation by DNA methylation. The encoded protein may be involved in regulation of organogenesis and myogenesis, and may play a role in premature ovarian failure. Multiple transcript variants encoding different isoforms have been found for this gene. DPABH-15501 is suitable for use in IHC (1:50–1:200) application. DPABH-15501 is supplied as a liquid formulation in pH7.4 PBS, 0.05% sodium azide, 40% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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