Recombinant human D2HGDH protein; Source: E. coli derived, PGEX-4T; Tag: GST; Domain: 1-286 aa of BC036604
Conjugate
Unconjugated
Applications
Application Notes
WB: 1:500-1:2000 IP: 0.5-4.0 μg for 1.0-3.0 mg of total protein lysate IHC: 1:50-1:500 IF/ICC: 1:20-1:200
General Notes
This product (Catalog No. DPABH-26831) is a rabbit-derived polyclonal antibody raised against human D2HGDH, targeting the amino acid region 1–286 of the protein. This antibody exhibits cross-reactivity with Human D2HGDH from mouse and rat. It has been affinity purified by Protein A. D2HGDH(D-2-hydroxyglutarate dehydrogenase, mitochondrial) is also named as D2HGD and belongs to the FAD-binding oxidoreductase/transferase type 4 family.It catalyzes the oxidation of D-2-hydroxyglutarate to alpha-ketoglutarate.Defects in D2HGDH are the cause of D-2-hydroxyglutaric aciduria type 1 (D2HGA1).It has 2 isoforms produced by alternative splicing. DPABH-26831 is suitable for use in Western blot (WB) (1:500–1:2,000), IP (0.5-4.0 μg for 1.0-3.0 mg of total protein lysate), IHC (1:50–1:500), IF/ICC (1:20–1:200) applications. DPABH-26831 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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